Common Reflex Pain Syndrome (CRPS), also known as Reflex Sympathetic Dystrophy, is a chronic, disabling, systemic disease that is characterized by severe pain, swelling and changes in skin color and temperature. It is an extremely painful and progressive syndrome that is often caused by injury to a peripheral nerve.
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CRPS is known to affect both males and females, but is three times more likely to occur in females versus males; the reason for this is unknown. According to the National Institute of Health, the average age for contracting CRPS is 40, but it has been diagnosed in children as young as two years old.